No fourth straight Final Four for Michigan State. The team it beat for the 2000 national title, Florida, is gone, too.
Still, in a respite from bracket-busting, most first-round games went according to form Friday.
The only true stunner was 12th-seeded Creighton's elimination of Florida 83-82 in double overtime on Terrell Taylor's 3-pointer with 0.2 seconds left in a Midwest Regional opener.
Add in Missouri's victory over Miami, and Tulsa's upset of Marquette -- both Thursday -- and it's the first time three No. 12s won first-round games in the same NCAA tourney.
"People make names for themselves when they win games like this," Creighton center Brody Deren said. "We have more to prove because we are a mid-major team, and we chalk this up for all the mid-majors."
Taylor -- wearing No. 23 in the United Center -- was 0-for-6 in the first half, but he turned it on the rest of the way. He was 8-for-10 from 3-point range after the break, and finished with 28 points to match his career high and give the Bluejays their first NCAA victory since 1999.
Creighton will face fourth-seeded Illinois, which rolled past San Diego State 93-64.
Even Michigan State's loss wasn't an upset, since the Spartans had a mediocre-for-them season and were seeded 10th in the East Regional. They lost to North Carolina State 69-58.
Held to a season-low 18 points in the first half, the Wolfpack took the ball straight to the basket in the second half to win their first NCAA tourney game in 11 years.
Freshman Ilian Evtimov scored 10 of his 12 points after the break for N.C. State.
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