Padres walk over Cardinals pitcher Jake Westbrook

ST. LOUIS -- Down two stars, the St. Louis Cardinals lost big-time.

Clayton Richard had two RBIs to match his career high without getting the ball out of the infield and pitched six solid innings in the San Diego Padres' 11-3 victory Saturday.

Albert Pujols homered on the 10th anniversary of his major league debut and Allen Craig, subbing for ailing Matt Holliday, had a two-run single for the Cardinals. St. Louis led 2-0 after one inning and 3-2 after three, but Jake Westbrook (0-1) was knocked out after retiring only one of six batters in the Padres' six-run sixth.

Even though Holliday is expected back in a week or so after undergoing an appendectomy Friday, it's another hit for a team that lost 20-game winner Adam Wainwright to reconstructive elbow surgery in February.

"You can't think about Matt because he's out of the lineup. Everybody knows that," Pujols said. "We need to go out there and those nine guys that Tony [La Russa] puts in the lineup, those are the guys that are going to do the job."

Cardinals starting pitcher Jake Westbrook delivers during the first inning Saturday.

Chase Headley tied his career high with four RBIs, including a two-run homer in the ninth for the Padres, who are 6-14 at six-year-old Busch Stadium but clinched their first series win in St. Louis since September 2006. They'll go for their first three-game sweep in St. Louis since June 23 to 25, 1980, today with Dustin Moseley facing Cardinals left-hander Jaime Garcia, who finished third in NL rookie of year voting but coming off a rough spring.

Cardinals pitchers totaled eight walks, two of them intentional, but also two with the bases loaded.

Three of the Cardinals' five hits off Richard (1-0) came in a first inning, including Craig's two-run single. The only other damage came from Pujols' first hit of the season, a drive into the visitors' bullpen leading off the third to put St. Louis ahead 3-2 and ended an 0 for 6 start that featured a career-worst three double-play balls in the opener.

Richard, who entered 2-9 with a 5.63 ERA on the road, allowed only two baserunners the rest of his outing.

Richard has nine career RBIs, including three two-run games. His perfectly executed squeeze bunt tied it at 2-2 in the second, and Jason Motte walked him on four pitches for the fifth run in the Padres' fifth.

A pair of infield hits, a sacrifice and an intentional walk loaded the bases in the fifth ahead of Ryan Ludwick's five-pitch, run-scoring walk to snap a 3-3 tie. Headley's two-run single chased Westbrook, whose five walks were one off his career worst.

"I feel great. It's just a matter of finding it, harnessing it and being more consistent," Westbrook said. "I was very excited but I've played long enough to where I was able to harness it.

"I wasn't too amped up, but bottom line I wasn't able to get the job done."