NFL: Week 4; Sunday's games

Chargers 41, Patriots 17

This was finally the week the New England Patriots couldn't plug the holes left by injuries -- not against Drew Brees and San Diego's explosive offense.

The Chargers (2-2) handed the Patriots (2-2) their first loss at Gillette Stadium in 22 games on Sunday, beating them 41-17 as Brees threw for two touchdowns, LaDainian Tomlinson ran for two more and Antonio Gates had six catches for 108 yards.

Tomlinson finished with 134 yards on 25 carries, and overall San Diego rushed for 183 yards.

Saints 19, Bills 7

The Alamodome certainly felt like home for the New Orleans Saints.

Aaron Brooks ran for a touchdown, John Carney kicked four field goals and the defense kept Buffalo's floundering offense bottled up after the first quarter. New Orleans (2-2) snapped a two-game losing streak in its temporary home after Hurricane Katrina forced the Saints from the Superdome.

Donte' Stallworth grabbed eight receptions for 129 yards and Deuce McAllister rushed for 130 yards for the Saints. J.P. Losman continued to struggle for Buffalo (1-3), going 7-of-15 for 75 yards with an interception and three sacks.

Bengals 16, Texans 10

The Bengals are 4-0 for the first time since 1988 -- the last time they went to the Super Bowl -- as T.J. Houshmandzadeh paced a bogged-down offense with 105 yards on eight catches.

Shayne Graham's 27-yard field goal with 5:04 left broke a 10-10 tie, and David Carr's fumble with 3:14 sent the Texans to their first 0-3 start in four seasons as an expansion team.

Colts 31, Titans 10

Peyton Manning threw for 264 yards and four touchdowns, including two to Marvin Harrison that tied the NFL record for most TDs between a quarterback and receiver.

Harrison caught nine passes for 109 yards, and Edgerrin James also ran for 90 yards in helping the Colts improve to 4-0 with their highest point total this season.

Manning and Harrison tied Steve Young and Jerry Rice for most touchdowns between a quarterback and receiver with 85 career TDs on a 24-yard pass with 13:09 left in the game.

The Titans fell to 1-3.

Redskins 20, Seahawks 17, OT

Rookie Nick Novak kicked a 39-yard field goal 5:31 into overtime to give the Redskins their first 3-0 start since 1991, the season they won their last Super Bowl.

The Seahawks (2-2) tied the game on Darrell Jackson's 6-yard catch with 1:23 remaining.

Broncos 20, Jaguars 7

Jake Plummer threw two touchdown passes to backup offensive lineman Dwayne Carswell, while Mike Anderson and Tatum Bell combined for 175 yards rushing.

The Broncos (3-1) won their third straight. The Jaguars (2-2) finished with a franchise-low 12 yards rushing.

Buccaneers 17, Lions 13

Joey Galloway scored on an 80-yard reception and Brian Griese threw for 302 yards as Tampa Bay got off to its first 4-0 start since 1997.

Rookie Carnell "Cadillac" Williams, slowed by a sore hamstring, was held to 13 yards on 11 carries.

Detroit (1-2) thought it would escape with a victory when Joey Harrington found Marcus Pollard in the right corner of the end zone, but the tight end's sliding catch was reversed by instant replay.

Eagles 37, Chiefs 31

Playing with a bruised chest, a sore leg and an aching abdominal strain, Donovan McNabb rallied the Eagles from an 18-point deficit.

The five-time Pro Bowl quarterback hit 33 of 48 passes for 369 yards and three touchdowns as the Eagles (3-1) scored 28 straight points. That run followed a 96-yard kickoff return by Dante Hall that put the Chiefs on top 24-6 with 4:27 left in the first half.

Terrell Owens fueled the comeback by consistently getting open, catching 11 passes for 171 yards and a TD. The Chiefs (2-2) closed within six points with 1:24 left on Trent Green's 15-yard TD pass to Hall, but the Eagles recovered the onside kick.

Raiders 19, Cowboys 13

LaMont Jordan ran for 126 yards and a score, Sebastian Janikowski kicked four field goals and Oakland's defense put together a late goal-line stand to lead the Raiders (1-3).

Trailing 19-13 after Janikowski's 43-yard field goal with 4:29 left, Dallas (2-2) drove inside the 5. But Tommy Kelly hit Julius Jones for a 2-yard loss on second down from the 3, and Bledsoe followed with two straight incompletions.

Falcons 30, Vikings 10

Michael Vick went down midway through the second quarter with a sprained right knee, watching the rest of the game from the sideline as backup Matt Schaub and the defense finished off the Falcons' rout.

Warrick Dunn rushed for 126 yards to lead a 274-yard performance on the ground. Vick ran for 58 yards and threw a touchdown pass before getting hurt. The Falcons' defense made things miserable for Daunte Culpepper, who was sacked nine times, intercepted twice and lost a fumble for the Vikings (1-3).

Ravens 13, Jets 3

Jamal Lewis scored on a 1-yard run, Matt Stover kicked two field goals, and the Ravens won their first game of the year.

The Ravens (1-2) held Curtis Martin to 30 yards on 13 carries, sacked third-string quarterback Brooks Bollinger five times and limited the Jets (1-3) to eight first downs and 152 yards.

-- From wire reports