1900-1909
1900 W.H. Meyer & Schwab Hardware established.
1900 George A. Kassel opened photography studio on Main, and began tintyping and making glass plate pictures.
1900 Leach Bros. Store closed.
1900-1904 The Republican was published with variety of owners.
1901-1904 The Daily News was published.
1902 Frisco Railroad bought Houck railroad.
1902 German-American Bank organized at 42 N. Main.
1902 Hely limestone quarry established.
1903 Tatum and Cross tobacco factory reorganized and building erected at 103 S. Frederick.
Circa 1903 Frank Morrison founded ice and fuel company.
1903 Cape Girardeau Bell Telephone Co. incorporated.
1904 The Daily Republican was purchased by Fred and George Naeter; began publishing in Opera House.
1904 The Daily Republican absorbed The Daily News.
1904 Riverview Hotel damaged by fire and rebuilt.
1904 Farmers and Merchants Bank incorporated; located at 632 Good Hope.
1904 William Gockel started motor-driven "red devil" between Jackson and Cape Girardeau, discarding horse-drawn stage coach.
1904 Lorimier Hotel burned; was owned by Louis Houck.
1904 Meyer Hardware building on Good Hope constructed.
1904 Fred H. Kassel established jewelry store.
1904 Cape Girardeau Business College organized by Professor J.W. Moothart.
1904 Lorimier Hotel reopened at Fountain and Elm.
1905 Roth Tobacco Co. opened its new building on South Frederick.
1905 First National Bank moved to new building at 117 N. Main.
1905 Southeast Missouri Trust Co. opened in H.-H. Building.
1905 Terminal Hotel opened.
1905 Diamond Restaurant opened.
1905 N.S. Weiler opened jewelry store.
1905 Pieronnet-Wilson Mercantile Co. formed.
1905 Juden-Lilly Mercantile Co. established.
1905 Catern & Haas opened fruit store.
1905 Riverview Hotel rebuilt.
1905 Diamond Cafe opened.
Circa 1905 E. and W. Shirt factory established.
1905 Street car company reorganized.
1905 The Daily Republican moved to Wilson house at corner of Broadway and Spanish.
1905 Central Labor Council organized.
1905 Catern & Haas fruit store closed.
1905 William P. Ettlin purchased Terminal Hotel bar.
1906 James A. Kinder Drug Store started.
1906 Roberts, Johnson and Rand Shoe factory plant built on North Main.
1906 T.B. Jones' Racket Store failed.
1906 Harley Shoe factory established.
1906 J.M. Shy and F.R. Cross entered grocery business.
1906 Southeast Missouri Fruit Co. incorporated.
1906 L.M. Culler sold Riverview Hotel for $75,000.
1906 Meyer Brothers Meat Market completed.
1906 R.B. Andrews opened grocery store.
1906 Tipton's Cleaners started at corner of Main and Independence.
1906 Brinkopf-Howell Furniture and Undertaking Co. founded.
1906 Finney's Drug Store established.
1907 First picture show shown in Cape Girardeau (in store room on Main Street).
1907 C.M. Buckner and W.B. Ragsdale purchased Flentge & Co. Store at Main and Broadway.
1907 Roberts, Johnson and Rand Shoe factory began operation.
1907 Bob Literer opened Arcade Nickelodeum.
1907 Dreamland Theater opened.
1907 Cape Amusement Co. organized, 23 Main Street; presented vaudeville entertainment and movies.
1907 Lyric Theater opened on Main Street.
1907 German-American Bank failed.
1907 Dreamland Theater closed and Lyric Theater changed its named to Dreamland Theater.
1907 Wulfers Bros. meat market opened.
1907 Print shop of George W. Cross, 116 Broadway, was destroyed by fire.
1907 Boston Store sold by John F. Schwepker.
1908 Southeast Missouri Trust Co. opened in H.-H. Building.
1908 D.A. Glenn, J.H. Himmelberger, George McBride and E.W. Flentge purchased controlling interest in Roth Tobacco Co.
1908 E. & W. Shirt factory closed.
1908 Smelting plant property sold by sheriff.
1908 Buckner-Ragsdale Store damaged by fire.
1908 F.H. Elfrank opened harness shop at 610 Good Hope.
1908 Terminal Hotel saloon closed by William Etling
1908 Emil Teichman and C.J. Winningham opened Boston Store at southwest corner of Main and Broadway.
1908 Kraft Home Steam Bakery opened on Good Hope by Fred H. Kraft.
1908 The Daily Republican moved into new building in 200 block of Broadway.
1908 City Drug Store was sold by Capt. F.L. Withaup to Joe N. Woolsey.
1908 Haman Drug Store established.
1908 Himmelberger-Harrison Building (H.-H. Building) constructed.
1909 First part of Idan Ha Hotel at southwest corner of Broadway and Fountain opened.
1909 Broadway Theater opened in store room.
1909 Southeast Realty Company chartered.
1909 Planters Flour Mill at south end of Main, on Independence, burned.
1909 Auto Tire & Parts opened on South Spanish.
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