COLUMBIA, Mo. -- James Franklin accounted for five touchdowns.
He got humbled a bit, too.
Franklin threw three touchdown passes and ran for two scores for Missouri in a 52-17 rout of Iowa State in the Tigers' 100th homecoming game Saturday. He was intercepted twice, and one of them was returned for a score.
"Those were very poor decisions by James, and the great thing about that is he came back," Tigers coach Gary Pinkel said. "Body language-wise, he was disappointed how he let the team down.
"The good news is how you respond to it, and I thought he did a great job of coming out of that and executing our offense."
Michael Egnew, T.J. Moe and Wes Kemp each had a scoring reception for Missouri (3-3, 1-2 Big 12), which scored on its first four possessions. Much of a sellout crowd of 71,004 had dispersed by the end of the Tigers' 10th consecutive victory at home and their first game at Faurot Field in a month.
"It's always good to start fast and be able to move the ball and score points like that," Franklin said. "They're going to make plays, too, so I think we did a good job putting our mistakes behind us."
It was the most lopsided setback of the year for Iowa State (3-3, 0-3). A.J. Klein's 78-yard interception return for a touchdown was the lone highlight for the Cyclones, who have been outscored 54-10 in the first quarter, including by 21 on Saturday.
"They were a dangerous football team waiting to explode," Iowa State coach Paul Rhoads said. "They did it twice with long fields, they did it twice with short fields and made mincemeat out of our football team."
Iowa State's James White was held to 61 yards on 14 carries a week after getting a career-best 148 yards against Baylor. White had 10 yards on 10 carries in the first three quarters.
Missouri had no penalty yardage in its fifth consecutive victory in the series. Linebacker Luke Lambert had two fumble recoveries.
The Tigers play No. 6 Oklahoma State next week.
"If we're very focused, we can be pretty good," Pinkel said. "And if we're not focused, we can be very average. Everybody's got to be locked in."
After scoring on the first four drives for a 28-3 cushion, the Tigers turned it over in the passing game the next three times but were hurt only by Klein's third career touchdown. The Tigers had 298 yards rushing one week after managing just 112 yards in a loss at No. 17 Kansas State.
"We need to become more focused for games like this, to go out there and give everything we have," Iowa State linebacker Jake Knott said. "We thought we had fixed everything. They found another weakness, so we're going to have to go back and fix that weakness."
Missouri defensive tackle Terrell Resonno sprained his right knee during the first half and did not return. Pinkel said the extent of the injury was not yet clear. The 295-pound senior has started all 14 games over the last two seasons and had 15 tackles and a sack in the Tigers' first five games.
Franklin was 20 of 28 for 289 yards and three touchdowns and rushed for 84 yards on 11 carries with two scores. Josey had 129 yards on 19 carries for his third 100-yard game of the year.
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