One killed, 3 injured in crash in Fredericktown, Mo.

MARBLE HILL, Mo. -- A 22-year-old Marble Hill man died and a woman and two children were hospitalized after an accident Friday afternoon in Fredericktown, Mo.

Jesse Wayne James was eastbound in a red Dodge pickup on Highway 72 in front of the intermediate school about 4 p.m. when he ran off the road, Capt. Eric Hovis said. The vehicle struck a culvert, spun out and rolled over, Hovis said.

James was partially ejected from the pickup. He was pronounced dead at the scene, Hovis said. His unidentified 22-year-old girlfriend suffered serious injuries and was hospitalized. Two children, ages 1 and 3, were hospitalized.

Hovis, one of the first emergency personnel on the scene, said the pickup was upside down when he arrived and the children were in their safety seats.