Red Letter Communications will move its operations to 16 N. Spanish Street in Cape Girardeau.
The advertising agency, which employs about 50 people, is currently located at 231 N. Main Street.
The two-story, 13,000-square-foot building will be renovated with help from Keystone Design of Cape Girardeau. A contractor has not been selected at this time.
The move coincides with the company's 30th anniversary.
"Red Letter has grown significantly in terms of clients, assignments and staffing," said founder and CEO Jim Riley. "We love the current location, but found ourselves sitting on each others' laps. This new facility will double the available space."
The company hopes to move into its new building, formerly home of Stev-Mark Gallery and Cape Importers, next spring.
"I invite other business owners to consider downtown for their next location," said Riley. "Being downtown has helped define the character of our company. I can't imagine us anywhere else."
Red Letter management was joined by representatives of Old Town Cape, the City of Cape Girardeau, and the Cape Girardeau Area Chamber of Commerce and the Southeast Missouri State Center for Innovation and Entrepreneurship during a news conference to announce the move Wednesday.
To learn more about the company, visit http://rlci.com.